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A Steep Radioiodine Dose Response Scalable to Humans in Sodium Iodide Symporter (NIS) Mediated Radiovirotherapy for Prostate Cancer

The sodium iodide symporter (NIS) directs the uptake and concentration of iodide in thyroid cells. We have extended the use of NIS-mediated radioiodine therapy to prostate cancer. We have developed a prostate tumor specific conditionally replicating adenovirus (CRAd) that expresses hNIS (Ad5PB_RSV-N...

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Detalles Bibliográficos
Autores principales:	Trujillo, Miguel A., Oneal, Michael J., McDonough, Samantha, Qin, Rui, Morris, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499676/ https://www.ncbi.nlm.nih.gov/pubmed/23037808 http://dx.doi.org/10.1038/cgt.2012.68

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