A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon

Nonviral vector systems are used increasingly in gene targeting and gene transfer applications. The piggyBac transposon represents an alternative integrating vector for in vivo gene transfer. We hypothesized that this system could achieve persistent gene transfer to the liver when administered syste...

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Detalles Bibliográficos
Autores principales: Burnight, Erin R, Staber, Janice M, Korsakov, Pavel, Li, Xianghong, Brett, Benjamin T, Scheetz, Todd E, Craig, Nancy L, McCray, Paul B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499692/
https://www.ncbi.nlm.nih.gov/pubmed/23344650
http://dx.doi.org/10.1038/mtna.2012.12

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