Cargando…

MYCN: from oncoprotein to tumor-associated antigen

MYCN is a well-known oncogene over-expressed in different human malignancies including neuroblastoma (NB), rhabdomyosarcoma, medulloblastoma, astrocytoma, Wilms’ tumor, and small cell lung cancer. In the case of NB, MYCN amplification is an established biomarker of poor-prognosis. MYCN belongs to a...

Descripción completa

Detalles Bibliográficos
Autores principales: Pistoia, Vito, Morandi, Fabio, Pezzolo, Annalisa, Raffaghello, Lizzia, Prigione, Ignazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499703/
https://www.ncbi.nlm.nih.gov/pubmed/23162796
http://dx.doi.org/10.3389/fonc.2012.00174