Cargando…

The VPAC1 receptor: structure and function of a class B GPCR prototype

The class B G protein-coupled receptors (GPCRs) represents a small sub-family encompassing 15 members, and are very promising targets for the development of drugs to treat many diseases such as chronic inflammation, neurodegeneration, diabetes, stress, and osteoporosis. The VPAC1 receptor which is a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Couvineau, A., Ceraudo, E., Tan, Y.-V., Nicole, P., Laburthe, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499705/ https://www.ncbi.nlm.nih.gov/pubmed/23162538 http://dx.doi.org/10.3389/fendo.2012.00139

Ejemplares similares

Editorial: GPCR in Inflammatory and Cancer Diseases
por: Couvineau, Alain, et al.
Publicado: (2020)

Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function
por: Peyrassol, Xavier, et al.
Publicado: (2018)

An Overview of VPAC Receptors in Rheumatoid Arthritis: Biological Role and Clinical Significance
por: Gomariz, Rosa P., et al.
Publicado: (2019)

Mechanisms involved in VPAC receptors activation and regulation: lessons from pharmacological and mutagenesis studies
por: Langer, Ingrid
Publicado: (2012)

Therapeutic potential of vasoactive intestinal peptide and its receptor VPAC2 in type 2 diabetes
por: Hou, Xintong, et al.
Publicado: (2022)

The Orexin receptors: Structural and anti-tumoral properties
por: Couvineau, Alain, et al.
Publicado: (2022)

Role of VPAC1 and VPAC2 receptors in the etiology of pregnancy rhinitis: an experimental study in rats
por: Ulkumen, Burak, et al.
Publicado: (2020)

A Web Server for GPCR-GPCR Interaction Pair Prediction
por: Nemoto, Wataru, et al.
Publicado: (2022)

Biophysical Detection of Diversity and Bias in GPCR Function
por: Jaeger, Werner C., et al.
Publicado: (2014)

Corrigendum: A Web Server for GPCR-GPCR Interaction Pair Prediction
por: Nemoto, Wataru, et al.
Publicado: (2022)

GPCR heteromers: An overview of their classification, function and physiological relevance
por: Dale, Natasha C., et al.
Publicado: (2022)

GPCR Heterodimerization in the Reproductive System: Functional Regulation and Implication for Biodiversity
por: Satake, Honoo, et al.
Publicado: (2013)

PAC(1), VPAC(1), and VPAC(2) Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies
por: Tasma, Zoe, et al.
Publicado: (2022)

Editorial: A year in review: discussions in molecular and structural endocrinology
por: Couvineau, Alain, et al.
Publicado: (2023)

Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity
por: Roed, Sarah Norklit, et al.
Publicado: (2012)

Probing GPCR Dimerization Using Peptides
por: Farooq, Zara, et al.
Publicado: (2022)

Understanding VPAC receptor family peptide binding and selectivity
por: Piper, Sarah J., et al.
Publicado: (2022)

Intracellular VHHs to monitor and modulate GPCR signaling
por: Raynaud, Pauline, et al.
Publicado: (2022)

Editorial: New approaches for the discovery of GPCR ligands
por: Morales, Paula, et al.
Publicado: (2023)

Diagnosis of Oral Cancers by Targeting VPAC Receptors: Preliminary Report
por: Nerli, Rajendra, et al.
Publicado: (2023)

Diversity and Bias through Receptor–Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization
por: Fuxe, Kjell, et al.
Publicado: (2014)

Structural–Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work
por: Kleinau, Gunnar, et al.
Publicado: (2017)

Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System
por: Kamal, Maud, et al.
Publicado: (2011)

Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases
por: Couvineau, Alain, et al.
Publicado: (2019)

Receptor oligomerization: from early evidence to current understanding in class B GPCRs
por: Ng, Stephanie Y. L., et al.
Publicado: (2013)

BRET biosensors to study GPCR biology, pharmacology, and signal transduction
por: Salahpour, Ali, et al.
Publicado: (2012)

Regulation of FGF2-induced proliferation by inhibitory GPCR in normal pituitary cells
por: Sosa, Liliana del V., et al.
Publicado: (2023)

Class B1 GPCR activation by an intracellular agonist
por: Kobayashi, Kazuhiro, et al.
Publicado: (2023)

GPCR-mediated effects of fatty acids and bile acids on glucose homeostasis
por: Oteng, Antwi-Boasiako, et al.
Publicado: (2023)

Seasonal changes in the expression of PACAP, VPAC1, VPAC2, PAC1 and testicular activity in the testis of the muskrat (Ondatra zibethicus)
por: Tang, Zeqi, et al.
Publicado: (2022)

The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role
por: Couvineau, Alain, et al.
Publicado: (2018)

Understanding Ligand Binding Selectivity in a Prototypical GPCR Family
por: Mattedi, Giulio, et al.
Publicado: (2019)

Phase-plate cryo-EM structure of a class B GPCR-G protein complex
por: Liang, Yi-Lynn, et al.
Publicado: (2017)

The stimulatory effect of the octadecaneuropeptide ODN on astroglial antioxidant enzyme systems is mediated through a GPCR
por: Hamdi, Yosra, et al.
Publicado: (2012)

Multiplexed analysis of the secretin-like GPCR-RAMP interactome
por: Lorenzen, Emily, et al.
Publicado: (2019)

VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus
por: Fung, Candice, et al.
Publicado: (2017)

Detection of bladder cancer using voided urine sample and by targeting genomic VPAC receptors
por: Nerli, Rajendra B., et al.
Publicado: (2021)

Molecular Basis of Class B GPCR Selectivity for the Neuropeptides PACAP and VIP
por: Liao, Chenyi, et al.
Publicado: (2021)

Structural Mapping and Functional Characterization of Zebrafish Class B G-Protein Coupled Receptor (GPCR) with Dual Ligand Selectivity towards GLP-1 and Glucagon
por: Oren, Deena A., et al.
Publicado: (2016)

The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor Activation
por: Winfield, Ian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q994ek39g26dc59l7rhlgas0kj