Effect of particle size on solubility, dissolution rate, and oral bioavailability: evaluation using coenzyme Q(10) as naked nanocrystals

In this paper work, four naked nanocrystals (size range 80–700 nm) were prepared without any surfactant or polymer using the solvent/nonsolvent method. The effects of particle size on their solubility, dissolution, and oral bioavailability were investigated. Solubility and dissolution testing were p...

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Detalles Bibliográficos
Autores principales: Sun, Jiao, Wang, Fan, Sui, Yue, She, Zhennan, Zhai, Wenjun, Wang, Chunling, Deng, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500035/
https://www.ncbi.nlm.nih.gov/pubmed/23166438
http://dx.doi.org/10.2147/IJN.S34365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500035/
https://www.ncbi.nlm.nih.gov/pubmed/23166438
http://dx.doi.org/10.2147/IJN.S34365

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