Cooperativity of Rb, Brca1, and p53 in Malignant Breast Cancer Evolution

Breast cancers that are “triple-negative” for the clinical markers ESR1, PGR, and HER2 typically belong to the Basal-like molecular subtype. Defective Rb, p53, and Brca1 pathways are each associated with triple-negative and Basal-like subtypes. Our mouse genetic studies demonstrate that the combined...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Prashant, Mukherjee, Malini, Johnson, Jacob P. S., Patel, Milan, Huey, Bing, Albertson, Donna G., Simin, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500050/
https://www.ncbi.nlm.nih.gov/pubmed/23173005
http://dx.doi.org/10.1371/journal.pgen.1003027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500050/
https://www.ncbi.nlm.nih.gov/pubmed/23173005
http://dx.doi.org/10.1371/journal.pgen.1003027

Ejemplares similares