Cargando…
Golgicide A reveals essential roles for GBF1 in Golgi assembly and function
ADP-ribosylation factor 1 (Arf1) plays a critical role in regulating secretory traffic and membrane transport within the Golgi of eukaryotic cells. Arf1 is activated by guanine nucleotide exchange factors (ArfGEFs) which confer spatial and temporal specificity to vesicular transport. We describe her...
Autores principales: | Saenz, Jose B., Sun, William J., Chang, Jae Won, Li, Jinmei, Bursulaya, Badry, Gray, Nathanael S., Haslam, David B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500152/ https://www.ncbi.nlm.nih.gov/pubmed/19182783 http://dx.doi.org/10.1038/nchembio.144 |
Ejemplares similares
-
Site-specific phosphorylations of the Arf activator GBF1 differentially regulate GBF1 function in Golgi homeostasis and secretion versus cytokinesis
por: Walton, Kendall, et al.
Publicado: (2023) -
A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport
por: Lopes-da-Silva, Mafalda, et al.
Publicado: (2019) -
De Novo and Inherited Variants in GBF1 are Associated with Axonal Neuropathy Caused by Golgi Fragmentation
por: Mendoza-Ferreira, Natalia, et al.
Publicado: (2020) -
The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi
por: Meissner, Justyna M., et al.
Publicado: (2023) -
The Arf-GDP-regulated recruitment of GBF1 to Golgi membranes requires domains HDS1 and HDS2 and a Golgi-localized protein receptor
por: Quilty, Douglas, et al.
Publicado: (2019)