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A biophysical mechanism may control the collinearity of Hoxd genes during the early phase of limb development

A biophysical model has been proposed which deals with the observed collinearity of Hox gene expressions in developing vertebrate limbs. It is assumed that physical forces gradually dislocate the genes of the Hoxd cluster from inside the chromosome territory into the interchromosome domain, where th...

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Detalles Bibliográficos
Autor principal: Papageorgiou, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500206/
https://www.ncbi.nlm.nih.gov/pubmed/19403461
http://dx.doi.org/10.1186/1479-7364-3-3-275