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Different fatty acid metabolism effects of (−)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung cancer

BACKGROUND: Fatty acid synthase (FASN) is overexpressed and hyperactivated in several human carcinomas, including lung cancer. We characterize and compare the anti-cancer effects of the FASN inhibitors C75 and (−)-epigallocatechin-3-gallate (EGCG) in a lung cancer model. METHODS: We evaluated in vit...

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Detalles Bibliográficos
Autores principales:	Relat, Joana, Blancafort, Adriana, Oliveras, Glòria, Cufí, Sílvia, Haro, Diego, Marrero, Pedro F, Puig, Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500220/ https://www.ncbi.nlm.nih.gov/pubmed/22769244 http://dx.doi.org/10.1186/1471-2407-12-280

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