BCL::Fold - De Novo Prediction of Complex and Large Protein Topologies by Assembly of Secondary Structure Elements

Computational de novo protein structure prediction is limited to small proteins of simple topology. The present work explores an approach to extend beyond the current limitations through assembling protein topologies from idealized α-helices and β-strands. The algorithm performs a Monte Carlo Metrop...

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Detalles Bibliográficos
Autores principales: Karakaş, Mert, Woetzel, Nils, Staritzbichler, Rene, Alexander, Nathan, Weiner, Brian E., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500284/
https://www.ncbi.nlm.nih.gov/pubmed/23173050
http://dx.doi.org/10.1371/journal.pone.0049240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500284/
https://www.ncbi.nlm.nih.gov/pubmed/23173050
http://dx.doi.org/10.1371/journal.pone.0049240

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