Epithelial-Mesenchymal-Transition-Like and TGFβ Pathways Associated with Autochthonous Inflammatory Melanoma Development in Mice

We compared gene expression signatures of aggressive amelanotic (Amela) melanomas with those of slowly growing pigmented melanomas (Mela), identifying pathways potentially responsible for the aggressive Amela phenotype. Both tumors develop in mice upon conditional deletion in melanocytes of Ink4a/Ar...

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Detalles Bibliográficos
Autores principales: Wehbe, Maria, Soudja, Saïdi M., Mas, Amandine, Chasson, Lionel, Guinamard, Rodolphe, de Tenbossche, Céline Powis, Verdeil, Grégory, Van den Eynde, Benoît, Schmitt-Verhulst, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500287/
https://www.ncbi.nlm.nih.gov/pubmed/23173060
http://dx.doi.org/10.1371/journal.pone.0049419

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