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Selective analysis of cell-free DNA in maternal blood for evaluation of fetal trisomy

OBJECTIVE: To develop a novel prenatal assay based on selective analysis of cell-free DNA in maternal blood for evaluation of fetal Trisomy 21 (T21) and Trisomy 18 (T18). METHODS: Two hundred ninety-eight pregnancies, including 39 T21 and seven T18 confirmed fetal aneuploidies, were analyzed using a...

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Detalles Bibliográficos
Autores principales: Sparks, Andrew B, Wang, Eric T, Struble, Craig A, Barrett, Wade, Stokowski, Renee, McBride, Celeste, Zahn, Jacob, Lee, Kevin, Shen, Naiping, Doshi, Jigna, Sun, Michel, Garrison, Jill, Sandler, Jay, Hollemon, Desiree, Pattee, Patrick, Tomita-Mitchell, Aoy, Mitchell, Michael, Stuelpnagel, John, Song, Ken, Oliphant, Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500507/
https://www.ncbi.nlm.nih.gov/pubmed/22223233
http://dx.doi.org/10.1002/pd.2922