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Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

The cholesterol-dependent cytolysins (CDCs) attack cells by punching large holes in their membranes. Lectinolysin from Streptococcus mitis is unique among CDCs due to the presence of an N-terminal lectin domain that enhances the pore-forming activity of the toxin. We recently determined the crystal...

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Detalles Bibliográficos
Autores principales:	Lawrence, Sara L., Feil, Susanne C., Holien, Jessica K., Kuiper, Michael J., Doughty, Larissa, Dolezal, Olan, Mulhern, Terrence D., Tweten, Rodney K., Parker, Michael W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500998/ https://www.ncbi.nlm.nih.gov/pubmed/23181061 http://dx.doi.org/10.3389/fimmu.2012.00330

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