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REST-dependent epigenetic remodeling promotes the in vivo developmental switch in NMDA receptors
N-methyl-D-aspartate receptors (NMDARs) are critical to synaptogenesis, neural circuitry and higher cognitive functions such as learning and memory. A hallmark feature of NMDARs is an early postnatal developmental switch from primarily GluN2B- to GluN2A-containing. Although the switch in phenotype h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501125/ https://www.ncbi.nlm.nih.gov/pubmed/22960932 http://dx.doi.org/10.1038/nn.3214 |