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Non-proteinogenic Amino Acids in Lacticin 481 Analogues Result in More Potent Inhibition of Peptidoglycan Transglycosylation
[Image: see text] Lantibiotics are ribosomally synthesized and post-translationally modified peptide natural products that contain the thioether structures lanthionine and methyllanthionine and exert potent antimicrobial activity against Gram-positive bacteria. At present, detailed modes-of-action a...
Autores principales: | Knerr, Patrick J., Oman, Trent J., Garcia De Gonzalo, Chantal V., Lupoli, Tania J., Walker, Suzanne, van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501146/ https://www.ncbi.nlm.nih.gov/pubmed/22920239 http://dx.doi.org/10.1021/cb300372b |
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