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T-bet(+) Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2

Foxp3(+) regulatory T (Treg) cells limit inflammatory responses and maintain immune homeostasis. Although comprised of several phenotypically and functionally distinct subsets, the differentiation of specialized Treg cell populations within the periphery is poorly characterized. We demonstrate that...

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Detalles Bibliográficos
Autores principales:	Koch, Meghan A., Thomas, Kerri R., Perdue, Nikole R., Smigiel, Kate S., Srivastava, Shivani, Campbell, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501343/ https://www.ncbi.nlm.nih.gov/pubmed/22960221 http://dx.doi.org/10.1016/j.immuni.2012.05.031

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