Novel MeCP2 Isoform-Specific Antibody Reveals the Endogenous MeCP2E1 Expression in Murine Brain, Primary Neurons and Astrocytes

Rett Syndrome (RTT) is a severe neurological disorder in young females, and is caused by mutations in the X-linked MECP2 gene. MECP2/Mecp2 gene encodes for two protein isoforms; MeCP2E1 and MeCP2E2 that are identical except for the N-terminus region of the protein. In brain, MECP2E1 transcripts are...

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Detalles Bibliográficos
Autores principales: Zachariah, Robby M., Olson, Carl O., Ezeonwuka, Chinelo, Rastegar, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501454/
https://www.ncbi.nlm.nih.gov/pubmed/23185431
http://dx.doi.org/10.1371/journal.pone.0049763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501454/
https://www.ncbi.nlm.nih.gov/pubmed/23185431
http://dx.doi.org/10.1371/journal.pone.0049763

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