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Increased Expression of the Very Low-Density Lipoprotein Receptor Mediates Lipid Accumulation in Clear-Cell Renal Cell Carcinoma

Clear-cell renal cell carcinoma (RCC) is, in most cases, caused by loss of function of the tumor suppressor gene von Hippel–Lindau, resulting in constitutive activation of hypoxia-inducible factor (HIF)-1α and expression of hypoxia-induced genes in normoxic conditions. Clear-cell RCC cells are chara...

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Detalles Bibliográficos
Autores principales:	Sundelin, Jeanna Perman, Ståhlman, Marcus, Lundqvist, Annika, Levin, Max, Parini, Paolo, Johansson, Martin E., Borén, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501495/ https://www.ncbi.nlm.nih.gov/pubmed/23185271 http://dx.doi.org/10.1371/journal.pone.0048694

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