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Unexpected Relationships and Inbreeding in HapMap Phase III Populations

Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap pha...

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Detalles Bibliográficos
Autores principales: Stevens, Eric L., Baugher, Joseph D., Shirley, Matthew D., Frelin, Laurence P., Pevsner, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501496/
https://www.ncbi.nlm.nih.gov/pubmed/23185369
http://dx.doi.org/10.1371/journal.pone.0049575

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