Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes

To identify epigenetic patterns, which may predispose to type 2 diabetes (T2D) due to a family history (FH) of the disease, we analyzed DNA methylation genome-wide in skeletal muscle from individuals with (FH(+)) or without (FH(−)) an FH of T2D. We found differential DNA methylation of genes in biol...

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Detalles Bibliográficos
Autores principales: Nitert, Marloes Dekker, Dayeh, Tasnim, Volkov, Peter, Elgzyri, Targ, Hall, Elin, Nilsson, Emma, Yang, Beatrice T., Lang, Stefan, Parikh, Hemang, Wessman, Ylva, Weishaupt, Holger, Attema, Joanne, Abels, Mia, Wierup, Nils, Almgren, Peter, Jansson, Per-Anders, Rönn, Tina, Hansson, Ola, Eriksson, Karl-Fredrik, Groop, Leif, Ling, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501844/
https://www.ncbi.nlm.nih.gov/pubmed/23028138
http://dx.doi.org/10.2337/db11-1653

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