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AMP-Activated Protein Kinase α1 Protects Against Diet-Induced Insulin Resistance and Obesity

AMP-activated protein kinase (AMPK) is an essential sensor of cellular energy status. Defects in the α2 catalytic subunit of AMPK (AMPKα1) are associated with metabolic syndrome. The current study investigated the role AMPKα1 in the pathogenesis of obesity and inflammation using male AMPKα1-deficent...

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Detalles Bibliográficos
Autores principales: Zhang, Weiyu, Zhang, Xianling, Wang, Huan, Guo, Xin, Li, Honggui, Wang, Ying, Xu, Xin, Tan, Lyhun, Mashek, Mara T., Zhang, Chunxiang, Chen, Yingjie, Mashek, Douglas G., Foretz, Marc, Zhu, Chuhong, Zhou, Huaijun, Liu, Xu, Viollet, Benoit, Wu, Chaodong, Huo, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501873/
https://www.ncbi.nlm.nih.gov/pubmed/22829451
http://dx.doi.org/10.2337/db11-1373