Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease

Axonal degeneration is one of the earliest features of Parkinson’s disease pathology, which is followed by neuronal death in the substantia nigra and other parts of the brain. Inhibition of axonal degeneration combined with cellular neuroprotection therefore seem key to targeting an early stage in P...

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Detalles Bibliográficos
Autores principales: Tönges, Lars, Frank, Tobias, Tatenhorst, Lars, Saal, Kim A., Koch, Jan C., Szegő, Éva M., Bähr, Mathias, Weishaupt, Jochen H., Lingor, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501973/
https://www.ncbi.nlm.nih.gov/pubmed/23087045
http://dx.doi.org/10.1093/brain/aws254

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