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Acid extrusion via blood–brain barrier causes brain alkalosis and seizures after neonatal asphyxia
Birth asphyxia is often associated with a high seizure burden that is predictive of poor neurodevelopmental outcome. The mechanisms underlying birth asphyxia seizures are unknown. Using an animal model of birth asphyxia based on 6-day-old rat pups, we have recently shown that the seizure burden is l...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501974/ https://www.ncbi.nlm.nih.gov/pubmed/23125183 http://dx.doi.org/10.1093/brain/aws257 |