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Identification and characterization of peptide: N- glycanase from Dictyostelium discoideum

BACKGROUND: Peptide: N- glycanase (PNGase) enzyme cleaves oligosaccharides from the misfolded glycoproteins and prepares them for degradation. This enzyme plays a role in the endoplasmic reticulum associated degradation (ERAD) pathway in yeast and mice but its biological importance and role in multi...

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Detalles Bibliográficos
Autores principales: Gosain, Anuradha, Lohia, Rakhee, Shrivastava, Anju, Saran, Shweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502110/
https://www.ncbi.nlm.nih.gov/pubmed/22682495
http://dx.doi.org/10.1186/1471-2091-13-9