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Activation of extracellular signal-regulated protein kinase 5 is essential for cystitis- and nerve growth factor-induced calcitonin gene-related peptide expression in sensory neurons

BACKGROUND: Cystitis causes considerable neuronal plasticity in the primary afferent pathways. The molecular mechanism and signal transduction underlying cross talk between the inflamed urinary bladder and sensory sensitization has not been investigated. RESULTS: In a rat cystitis model induced by c...

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Detalles Bibliográficos
Autores principales: Yu, Sharon J, Xia, Chun-mei, Kay, Jarren C, Qiao, Li-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502118/
https://www.ncbi.nlm.nih.gov/pubmed/22742729
http://dx.doi.org/10.1186/1744-8069-8-48