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Broadly reactive antibodies specific for Plasmodium falciparum MSP-1(19) are associated with the protection of naturally exposed children against infection

BACKGROUND: The 19 kDa C-terminal region of Plasmodium falciparum Merozoite Surface Protein-1 is a known target of naturally acquired humoral immunity and a malaria vaccine candidate. MSP-1(19) has four predominant haplotypes resulting in amino acid changes labelled EKNG, QKNG, QTSR and ETSR. IgG an...

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Detalles Bibliográficos
Autores principales:	Dent, Arlene E, Moormann, Ann M, Yohn, Christopher T, Kimmel, Rhonda J, Sumba, Peter O, Vulule, John, Long, Carole A, Narum, David L, Crabb, Brendan S, Kazura, James W, Tisch, Daniel J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502150/ https://www.ncbi.nlm.nih.gov/pubmed/22909378 http://dx.doi.org/10.1186/1475-2875-11-287

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