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Histone Deacetylase (HDAC) 1 Controls the Expression of Beta Defensin 1 in Human Lung Epithelial Cells

Deregulation of the expression human beta defensin 1 (DEFB1), an antimicrobial peptide, has been implicated in the pathogenesis of COPD and asthma. Since the molecular mechanisms that regulate DEFB1 gene expression are widely unknown, the epigenetic processes involved in the regulation of the consti...

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Detalles Bibliográficos
Autores principales: Kallsen, Kimberley, Andresen, Ellen, Heine, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502185/
https://www.ncbi.nlm.nih.gov/pubmed/23185513
http://dx.doi.org/10.1371/journal.pone.0050000