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Development of a perfusion chamber assay to study in real time the kinetics of thrombosis and the antithrombotic characteristics of antiplatelet drugs
BACKGROUND: Arterial thrombosis triggered by vascular injury is a balance between thrombus growth and thrombus fragmentation (dethrombosis). Unbalance towards thrombus growth can lead to vascular occlusion, downstream ischemia and tissue damage. Here we describe the development of a simple methodolo...
Autores principales: | Stephens, Gillian, He, Ming, Wong, Connie, Jurek, Marzena, Luedemann, Hans-Christian, Shapurian, Golnaz, Munnelly, Kevin, Muir, Craig, Conley, Pamela B, Phillips, David R, Andre, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502277/ https://www.ncbi.nlm.nih.gov/pubmed/22852789 http://dx.doi.org/10.1186/1477-9560-10-11 |
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