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Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres

Alternative Lengthening of Telomeres (ALT) is a non-telomerase mechanism of telomere lengthening that occurs in about 10% of cancers overall and is particularly common in astrocytic brain tumors and specific types of sarcomas. Somatic cell hybridization analyses have previously shown that normal tel...

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Detalles Bibliográficos
Autores principales:	Bower, Kylie, Napier, Christine E., Cole, Sara L., Dagg, Rebecca A., Lau, Loretta M. S., Duncan, Emma L., Moy, Elsa L., Reddel, Roger R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502299/ https://www.ncbi.nlm.nih.gov/pubmed/23185534 http://dx.doi.org/10.1371/journal.pone.0050062

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