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Longitudinal Imaging Studies of Tumor Microenvironment in Mice Treated with the mTOR Inhibitor Rapamycin

Rapamycin is an allosteric inhibitor of mammalian target of rapamycin, and inhibits tumor growth and angiogenesis. Recent studies suggested a possibility that rapamycin renormalizes aberrant tumor vasculature and improves tumor oxygenation. The longitudinal effects of rapamycin on angiogenesis and t...

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Detalles Bibliográficos
Autores principales: Saito, Keita, Matsumoto, Shingo, Yasui, Hironobu, Devasahayam, Nallathamby, Subramanian, Sankaran, Munasinghe, Jeeva P., Patel, Vyomesh, Gutkind, J. Silvio, Mitchell, James B., Krishna, Murali C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502528/
https://www.ncbi.nlm.nih.gov/pubmed/23185335
http://dx.doi.org/10.1371/journal.pone.0049456