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Longitudinal Imaging Studies of Tumor Microenvironment in Mice Treated with the mTOR Inhibitor Rapamycin
Rapamycin is an allosteric inhibitor of mammalian target of rapamycin, and inhibits tumor growth and angiogenesis. Recent studies suggested a possibility that rapamycin renormalizes aberrant tumor vasculature and improves tumor oxygenation. The longitudinal effects of rapamycin on angiogenesis and t...
Autores principales: | Saito, Keita, Matsumoto, Shingo, Yasui, Hironobu, Devasahayam, Nallathamby, Subramanian, Sankaran, Munasinghe, Jeeva P., Patel, Vyomesh, Gutkind, J. Silvio, Mitchell, James B., Krishna, Murali C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502528/ https://www.ncbi.nlm.nih.gov/pubmed/23185335 http://dx.doi.org/10.1371/journal.pone.0049456 |
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