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Numerical test concerning bone mass apposition under electrical and mechanical stimulus

This article proposes a model of bone remodeling that encompasses mechanical and electrical stimuli. The remodeling formulation proposed by Weinans and collaborators was used as the basis of this research, with a literature review allowing a constitutive model evaluating the permittivity of bone tis...

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Autores principales: Garzón-Alvarado, Diego A, Ramírez-Martínez, Angélica M, Cardozo de Martínez, Carmen Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502529/
https://www.ncbi.nlm.nih.gov/pubmed/22578031
http://dx.doi.org/10.1186/1742-4682-9-14
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author Garzón-Alvarado, Diego A
Ramírez-Martínez, Angélica M
Cardozo de Martínez, Carmen Alicia
author_facet Garzón-Alvarado, Diego A
Ramírez-Martínez, Angélica M
Cardozo de Martínez, Carmen Alicia
author_sort Garzón-Alvarado, Diego A
collection PubMed
description This article proposes a model of bone remodeling that encompasses mechanical and electrical stimuli. The remodeling formulation proposed by Weinans and collaborators was used as the basis of this research, with a literature review allowing a constitutive model evaluating the permittivity of bone tissue to be developed. This allowed the mass distribution that depends on mechanical and electrical stimuli to be obtained. The remaining constants were established through numerical experimentation. The results demonstrate that mass distribution is altered under electrical stimulation, generally resulting in a greater deposition of mass. In addition, the frequency of application of an electric field can affect the distribution of mass; at a lower frequency there is more mass in the domain. These numerical experiments open up discussion concerning the importance of the electric field in the remodeling process and propose the quantification of their effects.
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spelling pubmed-35025292012-11-27 Numerical test concerning bone mass apposition under electrical and mechanical stimulus Garzón-Alvarado, Diego A Ramírez-Martínez, Angélica M Cardozo de Martínez, Carmen Alicia Theor Biol Med Model Research This article proposes a model of bone remodeling that encompasses mechanical and electrical stimuli. The remodeling formulation proposed by Weinans and collaborators was used as the basis of this research, with a literature review allowing a constitutive model evaluating the permittivity of bone tissue to be developed. This allowed the mass distribution that depends on mechanical and electrical stimuli to be obtained. The remaining constants were established through numerical experimentation. The results demonstrate that mass distribution is altered under electrical stimulation, generally resulting in a greater deposition of mass. In addition, the frequency of application of an electric field can affect the distribution of mass; at a lower frequency there is more mass in the domain. These numerical experiments open up discussion concerning the importance of the electric field in the remodeling process and propose the quantification of their effects. BioMed Central 2012-05-11 /pmc/articles/PMC3502529/ /pubmed/22578031 http://dx.doi.org/10.1186/1742-4682-9-14 Text en Copyright ©2012 Garzón Alvarado et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Garzón-Alvarado, Diego A
Ramírez-Martínez, Angélica M
Cardozo de Martínez, Carmen Alicia
Numerical test concerning bone mass apposition under electrical and mechanical stimulus
title Numerical test concerning bone mass apposition under electrical and mechanical stimulus
title_full Numerical test concerning bone mass apposition under electrical and mechanical stimulus
title_fullStr Numerical test concerning bone mass apposition under electrical and mechanical stimulus
title_full_unstemmed Numerical test concerning bone mass apposition under electrical and mechanical stimulus
title_short Numerical test concerning bone mass apposition under electrical and mechanical stimulus
title_sort numerical test concerning bone mass apposition under electrical and mechanical stimulus
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502529/
https://www.ncbi.nlm.nih.gov/pubmed/22578031
http://dx.doi.org/10.1186/1742-4682-9-14
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