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Numerical test concerning bone mass apposition under electrical and mechanical stimulus
This article proposes a model of bone remodeling that encompasses mechanical and electrical stimuli. The remodeling formulation proposed by Weinans and collaborators was used as the basis of this research, with a literature review allowing a constitutive model evaluating the permittivity of bone tis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502529/ https://www.ncbi.nlm.nih.gov/pubmed/22578031 http://dx.doi.org/10.1186/1742-4682-9-14 |
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author | Garzón-Alvarado, Diego A Ramírez-Martínez, Angélica M Cardozo de Martínez, Carmen Alicia |
author_facet | Garzón-Alvarado, Diego A Ramírez-Martínez, Angélica M Cardozo de Martínez, Carmen Alicia |
author_sort | Garzón-Alvarado, Diego A |
collection | PubMed |
description | This article proposes a model of bone remodeling that encompasses mechanical and electrical stimuli. The remodeling formulation proposed by Weinans and collaborators was used as the basis of this research, with a literature review allowing a constitutive model evaluating the permittivity of bone tissue to be developed. This allowed the mass distribution that depends on mechanical and electrical stimuli to be obtained. The remaining constants were established through numerical experimentation. The results demonstrate that mass distribution is altered under electrical stimulation, generally resulting in a greater deposition of mass. In addition, the frequency of application of an electric field can affect the distribution of mass; at a lower frequency there is more mass in the domain. These numerical experiments open up discussion concerning the importance of the electric field in the remodeling process and propose the quantification of their effects. |
format | Online Article Text |
id | pubmed-3502529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35025292012-11-27 Numerical test concerning bone mass apposition under electrical and mechanical stimulus Garzón-Alvarado, Diego A Ramírez-Martínez, Angélica M Cardozo de Martínez, Carmen Alicia Theor Biol Med Model Research This article proposes a model of bone remodeling that encompasses mechanical and electrical stimuli. The remodeling formulation proposed by Weinans and collaborators was used as the basis of this research, with a literature review allowing a constitutive model evaluating the permittivity of bone tissue to be developed. This allowed the mass distribution that depends on mechanical and electrical stimuli to be obtained. The remaining constants were established through numerical experimentation. The results demonstrate that mass distribution is altered under electrical stimulation, generally resulting in a greater deposition of mass. In addition, the frequency of application of an electric field can affect the distribution of mass; at a lower frequency there is more mass in the domain. These numerical experiments open up discussion concerning the importance of the electric field in the remodeling process and propose the quantification of their effects. BioMed Central 2012-05-11 /pmc/articles/PMC3502529/ /pubmed/22578031 http://dx.doi.org/10.1186/1742-4682-9-14 Text en Copyright ©2012 Garzón Alvarado et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Garzón-Alvarado, Diego A Ramírez-Martínez, Angélica M Cardozo de Martínez, Carmen Alicia Numerical test concerning bone mass apposition under electrical and mechanical stimulus |
title | Numerical test concerning bone mass apposition under electrical and mechanical stimulus |
title_full | Numerical test concerning bone mass apposition under electrical and mechanical stimulus |
title_fullStr | Numerical test concerning bone mass apposition under electrical and mechanical stimulus |
title_full_unstemmed | Numerical test concerning bone mass apposition under electrical and mechanical stimulus |
title_short | Numerical test concerning bone mass apposition under electrical and mechanical stimulus |
title_sort | numerical test concerning bone mass apposition under electrical and mechanical stimulus |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502529/ https://www.ncbi.nlm.nih.gov/pubmed/22578031 http://dx.doi.org/10.1186/1742-4682-9-14 |
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