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Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons
Cognitive abilities and disorders unique to humans are thought to result from adaptively driven changes in brain transcriptomes, but little is known about the role of cis-regulatory changes affecting transcription start sites (TSS). Here, we mapped in human, chimpanzee, and macaque prefrontal cortex...
Autores principales: | Shulha, Hennady P., Crisci, Jessica L., Reshetov, Denis, Tushir, Jogender S., Cheung, Iris, Bharadwaj, Rahul, Chou, Hsin-Jung, Houston, Isaac B., Peter, Cyril J., Mitchell, Amanda C., Yao, Wei-Dong, Myers, Richard H., Chen, Jiang-fan, Preuss, Todd M., Rogaev, Evgeny I., Jensen, Jeffrey D., Weng, Zhiping, Akbarian, Schahram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502543/ https://www.ncbi.nlm.nih.gov/pubmed/23185133 http://dx.doi.org/10.1371/journal.pbio.1001427 |
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