Malaria research challenges in low prevalence settings

The prevalence of malaria has reduced significantly in some areas over the past decade. These reductions have made local elimination possible and the research agenda has shifted to this new priority. However, there are critical issues that arise when studying malaria in low transmission settings, pa...

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Detalles Bibliográficos
Autores principales: Stresman, Gillian, Kobayashi, Tamaki, Kamanga, Aniset, Thuma, Philip E, Mharakurwa, Sungano, Moss, William J, Shiff, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502576/
https://www.ncbi.nlm.nih.gov/pubmed/23098277
http://dx.doi.org/10.1186/1475-2875-11-353
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author Stresman, Gillian
Kobayashi, Tamaki
Kamanga, Aniset
Thuma, Philip E
Mharakurwa, Sungano
Moss, William J
Shiff, Clive
author_facet Stresman, Gillian
Kobayashi, Tamaki
Kamanga, Aniset
Thuma, Philip E
Mharakurwa, Sungano
Moss, William J
Shiff, Clive
author_sort Stresman, Gillian
collection PubMed
description The prevalence of malaria has reduced significantly in some areas over the past decade. These reductions have made local elimination possible and the research agenda has shifted to this new priority. However, there are critical issues that arise when studying malaria in low transmission settings, particularly identifying asymptomatic infections, accurate detection of individuals with microparasitaemic infections, and achieving a sufficient sample size to have an adequately powered study. These challenges could adversely impact the study of malaria elimination if they remain unanswered.
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spelling pubmed-35025762012-11-22 Malaria research challenges in low prevalence settings Stresman, Gillian Kobayashi, Tamaki Kamanga, Aniset Thuma, Philip E Mharakurwa, Sungano Moss, William J Shiff, Clive Malar J Commentary The prevalence of malaria has reduced significantly in some areas over the past decade. These reductions have made local elimination possible and the research agenda has shifted to this new priority. However, there are critical issues that arise when studying malaria in low transmission settings, particularly identifying asymptomatic infections, accurate detection of individuals with microparasitaemic infections, and achieving a sufficient sample size to have an adequately powered study. These challenges could adversely impact the study of malaria elimination if they remain unanswered. BioMed Central 2012-10-25 /pmc/articles/PMC3502576/ /pubmed/23098277 http://dx.doi.org/10.1186/1475-2875-11-353 Text en Copyright ©2012 Stresman et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Stresman, Gillian
Kobayashi, Tamaki
Kamanga, Aniset
Thuma, Philip E
Mharakurwa, Sungano
Moss, William J
Shiff, Clive
Malaria research challenges in low prevalence settings
title Malaria research challenges in low prevalence settings
title_full Malaria research challenges in low prevalence settings
title_fullStr Malaria research challenges in low prevalence settings
title_full_unstemmed Malaria research challenges in low prevalence settings
title_short Malaria research challenges in low prevalence settings
title_sort malaria research challenges in low prevalence settings
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502576/
https://www.ncbi.nlm.nih.gov/pubmed/23098277
http://dx.doi.org/10.1186/1475-2875-11-353
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