Detection of respiratory viruses in asymptomatic children undergoing allogeneic hematopoietic cell transplantation

Detection of respiratory viruses by molecular methods, in children without respiratory symptoms undergoing hematopoietic cell transplantation (HCT), has not been well described. A prospective study of 33 asymptomatic children detected respiratory viruses in 8 of 33 (24%) patients before HCT. Human r...

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Detalles Bibliográficos
Autores principales: Srinivasan, Ashok, Flynn, Patricia, Gu, Zhengming, Hartford, Christine, Lovins, Richard, Sunkara, Anusha, Srivastava, Deo K., Leung, Wing, Hayden, Randall T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502722/
https://www.ncbi.nlm.nih.gov/pubmed/22987475
http://dx.doi.org/10.1002/pbc.24314
Descripción
Sumario:Detection of respiratory viruses by molecular methods, in children without respiratory symptoms undergoing hematopoietic cell transplantation (HCT), has not been well described. A prospective study of 33 asymptomatic children detected respiratory viruses in 8 of 33 (24%) patients before HCT. Human rhinovirus (HRV) was detected in five patients, and human adenovirus (hADV) in three patients. Two additional patients shed HRV, and one shed human coronavirus (hCoV), post‐HCT. Two patients had co‐infections. Of the 11 asymptomatic patients where respiratory virus was detected, 3 (27%) later developed an upper respiratory tract infection, from the same virus. Pediatr Blood Cancer 2013; 60: 149–151. © 2012 Wiley Periodicals, Inc.

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