Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases

Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype a...

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Detalles Bibliográficos
Autores principales: Melikyan, G., Abdelrahman, M. H., D'Suoza, A., Akhtar, N., Elzouki, A. N., Hammoudeh, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502814/
https://www.ncbi.nlm.nih.gov/pubmed/23198244
http://dx.doi.org/10.1155/2012/515768
Descripción
Sumario:Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype and autoantibody provides circumstantial evidence that an autoimmune aetiology might be involved. We describe two cases of TM associated with anti-Ro (SSA) autoantibodies without connective tissue disease manifestations. The two patients were treated successfully with IV steroids and cyclophosphamide.

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