Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases

Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype a...

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Autores principales: Melikyan, G., Abdelrahman, M. H., D'Suoza, A., Akhtar, N., Elzouki, A. N., Hammoudeh, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502814/
https://www.ncbi.nlm.nih.gov/pubmed/23198244
http://dx.doi.org/10.1155/2012/515768
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author Melikyan, G.
Abdelrahman, M. H.
D'Suoza, A.
Akhtar, N.
Elzouki, A. N.
Hammoudeh, M.
author_facet Melikyan, G.
Abdelrahman, M. H.
D'Suoza, A.
Akhtar, N.
Elzouki, A. N.
Hammoudeh, M.
author_sort Melikyan, G.
collection PubMed
description Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype and autoantibody provides circumstantial evidence that an autoimmune aetiology might be involved. We describe two cases of TM associated with anti-Ro (SSA) autoantibodies without connective tissue disease manifestations. The two patients were treated successfully with IV steroids and cyclophosphamide.
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spelling pubmed-35028142012-11-29 Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases Melikyan, G. Abdelrahman, M. H. D'Suoza, A. Akhtar, N. Elzouki, A. N. Hammoudeh, M. Case Rep Rheumatol Case Report Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype and autoantibody provides circumstantial evidence that an autoimmune aetiology might be involved. We describe two cases of TM associated with anti-Ro (SSA) autoantibodies without connective tissue disease manifestations. The two patients were treated successfully with IV steroids and cyclophosphamide. Hindawi Publishing Corporation 2012 2012-11-13 /pmc/articles/PMC3502814/ /pubmed/23198244 http://dx.doi.org/10.1155/2012/515768 Text en Copyright © 2012 G. Melikyan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Melikyan, G.
Abdelrahman, M. H.
D'Suoza, A.
Akhtar, N.
Elzouki, A. N.
Hammoudeh, M.
Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases
title Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases
title_full Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases
title_fullStr Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases
title_full_unstemmed Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases
title_short Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases
title_sort transverse myelitis associated with anti-ro (ssa) autoantibodies: a record of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502814/
https://www.ncbi.nlm.nih.gov/pubmed/23198244
http://dx.doi.org/10.1155/2012/515768
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