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Computational Modeling of the Metabolic States Regulated by the Kinase Akt

Signal transduction and gene regulation determine a major reorganization of metabolic activities in order to support cell proliferation. Protein Kinase B (PKB), also known as Akt, participates in the PI3K/Akt/mTOR pathway, a master regulator of aerobic glycolysis and cellular biosynthesis, two activ...

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Detalles Bibliográficos
Autores principales: Mosca, Ettore, Alfieri, Roberta, Maj, Carlo, Bevilacqua, Annamaria, Canti, Gianfranco, Milanesi, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502886/
https://www.ncbi.nlm.nih.gov/pubmed/23181020
http://dx.doi.org/10.3389/fphys.2012.00418