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Computational Modeling of the Metabolic States Regulated by the Kinase Akt
Signal transduction and gene regulation determine a major reorganization of metabolic activities in order to support cell proliferation. Protein Kinase B (PKB), also known as Akt, participates in the PI3K/Akt/mTOR pathway, a master regulator of aerobic glycolysis and cellular biosynthesis, two activ...
Autores principales: | Mosca, Ettore, Alfieri, Roberta, Maj, Carlo, Bevilacqua, Annamaria, Canti, Gianfranco, Milanesi, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502886/ https://www.ncbi.nlm.nih.gov/pubmed/23181020 http://dx.doi.org/10.3389/fphys.2012.00418 |
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