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Exploitation of chick embryo environments to reprogram MYCN-amplified neuroblastoma cells to a benign phenotype, lacking detectable MYCN expression
Neuroblastoma is a paediatric cancer that arises from the sympathetic ganglia (SG) or adrenal gland. Tumours that occur in patients under 18 months of age have a particularly good prognosis and frequently undergo spontaneous regression. This led to the hypothesis that developmental cues in the young...
Autores principales: | Carter, R, Mullassery, D, See, V, Theocharatos, S, Pizer, B, Losty, P D, Jesudason, E, Moss, D J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503288/ https://www.ncbi.nlm.nih.gov/pubmed/23552815 http://dx.doi.org/10.1038/oncsis.2012.24 |
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