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Knockdown of hypoxia-inducible factor-1α accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell lines

This study was performed to clarify the role of hypoxia-inducible factor-1 α (HIF-1α) in the development of peritoneal dissemination in a xenograft mouse model of gastric cancer. HIF-1α knockdown (KD) and control (SC) gastric cancer cells, which were established using the MKN45 and MKN74 cell lines,...

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Detalles Bibliográficos
Autores principales:	HIRAKI, MASATSUGU, KITAJIMA, YOSHIHIKO, KAI, KEITA, NAKAMURA, JUN, HASHIGUCHI, KAZUYOSHI, NOSHIRO, HIROKAZU, MIYAZAKI, KOHJI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503539/ https://www.ncbi.nlm.nih.gov/pubmed/23181099 http://dx.doi.org/10.3892/etm.2012.600

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