Identification and characterization of naturally occurring splice variants of SAMHD1

BACKGROUND: Sterile Alpha Motif and HD domain-containing protein 1 (SAMHD1) is a recently identified host factor that restricts HIV-1 replication in dendritic and myeloid cells. SAMHD1 is a dNTPase that presumably reduces the cellular dNTP levels to levels too low for retroviral reverse transcriptio...

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Detalles Bibliográficos
Autores principales: Welbourn, Sarah, Miyagi, Eri, White, Tommy E, Diaz-Griffero, Felipe, Strebel, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503569/
https://www.ncbi.nlm.nih.gov/pubmed/23092512
http://dx.doi.org/10.1186/1742-4690-9-86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503569/
https://www.ncbi.nlm.nih.gov/pubmed/23092512
http://dx.doi.org/10.1186/1742-4690-9-86

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