Presentation of hemophagocytic lymphohistiocytosis due to a novel MUNC 13–4 mutation masked by partial therapeutic immunosuppression

Hemophagocytic lymphohistiocytosis is a potentially fatal disease characterized by excessive macrophage and lymphocyte activity. Patients can be affected following immune activation after an oncologic, autoimmune or infectious trigger. An associated gene mutation may be found which impairs cytolytic...

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Detalles Bibliográficos
Autores principales: Garrett, Jackie P-D, Fung, Irene, Rupon, Jeremy, Knight, Andrea, Mizesko, Melissa, Paessler, Michelle, Orange, Jordan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503647/
https://www.ncbi.nlm.nih.gov/pubmed/22554126
http://dx.doi.org/10.1186/1546-0096-10-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503647/
https://www.ncbi.nlm.nih.gov/pubmed/22554126
http://dx.doi.org/10.1186/1546-0096-10-13

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