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Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden
BACKGROUND: Hypertension is common among persons with type 2 diabetes. The aim of this study was to analyze the association between ethnicity and hypertension prevalence after adjusting for age, sex, Hba1c, total cholesterol, elevated triglycerides and hypertriglyceridemic waist. The study populatio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503694/ https://www.ncbi.nlm.nih.gov/pubmed/22937746 http://dx.doi.org/10.1186/1756-0500-5-474 |
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author | Taloyan, Marina Saleh-Stattin, Nuha Johansson, Sven-Erik Agréus, Lars Wändell, Per |
author_facet | Taloyan, Marina Saleh-Stattin, Nuha Johansson, Sven-Erik Agréus, Lars Wändell, Per |
author_sort | Taloyan, Marina |
collection | PubMed |
description | BACKGROUND: Hypertension is common among persons with type 2 diabetes. The aim of this study was to analyze the association between ethnicity and hypertension prevalence after adjusting for age, sex, Hba1c, total cholesterol, elevated triglycerides and hypertriglyceridemic waist. The study population consisted of 354 primary health care patients diagnosed with type 2 diabetes (173 Assyrians/Syrians and 181 Swedes) residing in Södertälje, Sweden. Unconditional logistic regression was used to analyze the data. RESULTS: Hypertension prevalence was higher among Swedes than Assyrians/Syrians, (77% versus 58%; p = 0.001). In the unadjusted logistic regression model, the odds ratio for hypertension in Swedes was twice as high than that in Assyrians/Syrians (OR = 2.44; 95% CI =1.54-3.86). In the age- and sex-adjusted model, odds ratio of hypertension was 2.25 (95% CI 1.41-3.60). After adjustments for total cholesterol was made, the odds ratio of hypertension decreased slightly to 1.73. When elevated triglycerides and hypertriglyceridemic waist were separately introduced, the odds ratio of hypertension was no longer significant between the ethnic groups (1.60 and 1.43 for triglycerides and hypertriglyceridemic waist respectively). In addition, advanced age – 60–69 years old (OR = 1.80, CI 95% 1.00-3.20) and ≥ 70 years old (OR = 2.88, CI 95% 1.40-5.93), elevated total cholesterol (OR = 1.48, CI 95% 1.12-1.95) and presents of hypertriglyceridemic waist (those with high WC and high TG) were significant confounding factors for the increased risk of hypertension independent of ethnicity. CONCLUSIONS: The crude differences in prevalence of hypertension between the Swedes and Assyrians/Syrians in our study population with type 2 diabetes were no longer significant when adjusting for high triglycerides levels or the presence of hypertriglyceridemic waist. |
format | Online Article Text |
id | pubmed-3503694 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35036942012-11-22 Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden Taloyan, Marina Saleh-Stattin, Nuha Johansson, Sven-Erik Agréus, Lars Wändell, Per BMC Res Notes Research Article BACKGROUND: Hypertension is common among persons with type 2 diabetes. The aim of this study was to analyze the association between ethnicity and hypertension prevalence after adjusting for age, sex, Hba1c, total cholesterol, elevated triglycerides and hypertriglyceridemic waist. The study population consisted of 354 primary health care patients diagnosed with type 2 diabetes (173 Assyrians/Syrians and 181 Swedes) residing in Södertälje, Sweden. Unconditional logistic regression was used to analyze the data. RESULTS: Hypertension prevalence was higher among Swedes than Assyrians/Syrians, (77% versus 58%; p = 0.001). In the unadjusted logistic regression model, the odds ratio for hypertension in Swedes was twice as high than that in Assyrians/Syrians (OR = 2.44; 95% CI =1.54-3.86). In the age- and sex-adjusted model, odds ratio of hypertension was 2.25 (95% CI 1.41-3.60). After adjustments for total cholesterol was made, the odds ratio of hypertension decreased slightly to 1.73. When elevated triglycerides and hypertriglyceridemic waist were separately introduced, the odds ratio of hypertension was no longer significant between the ethnic groups (1.60 and 1.43 for triglycerides and hypertriglyceridemic waist respectively). In addition, advanced age – 60–69 years old (OR = 1.80, CI 95% 1.00-3.20) and ≥ 70 years old (OR = 2.88, CI 95% 1.40-5.93), elevated total cholesterol (OR = 1.48, CI 95% 1.12-1.95) and presents of hypertriglyceridemic waist (those with high WC and high TG) were significant confounding factors for the increased risk of hypertension independent of ethnicity. CONCLUSIONS: The crude differences in prevalence of hypertension between the Swedes and Assyrians/Syrians in our study population with type 2 diabetes were no longer significant when adjusting for high triglycerides levels or the presence of hypertriglyceridemic waist. BioMed Central 2012-08-31 /pmc/articles/PMC3503694/ /pubmed/22937746 http://dx.doi.org/10.1186/1756-0500-5-474 Text en Copyright ©2012 Taloyan et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Taloyan, Marina Saleh-Stattin, Nuha Johansson, Sven-Erik Agréus, Lars Wändell, Per Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden |
title | Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden |
title_full | Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden |
title_fullStr | Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden |
title_full_unstemmed | Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden |
title_short | Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden |
title_sort | hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in sweden |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503694/ https://www.ncbi.nlm.nih.gov/pubmed/22937746 http://dx.doi.org/10.1186/1756-0500-5-474 |
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