Induction of Tumor Cell Death through Targeting Tubulin and Evoking Dysregulation of Cell Cycle Regulatory Proteins by Multifunctional Cinnamaldehydes

Multifunctional trans-cinnamaldehyde (CA) and its analogs display anti-cancer properties, with 2-benzoyloxycinnamaldehyde (BCA) and 5-fluoro-2-hydroxycinnamaldehyde (FHCA) being identified as the ortho-substituted analogs that possess potent anti-tumor activities. In this study, BCA, FHCA and a nove...

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Detalles Bibliográficos
Autores principales: Nagle, Amrita A., Gan, Fei-Fei, Jones, Gavin, So, Choon-Leng, Wells, Geoffrey, Chew, Eng-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503761/
https://www.ncbi.nlm.nih.gov/pubmed/23185555
http://dx.doi.org/10.1371/journal.pone.0050125

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