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Single Nucleotide Polymorphisms in MCP-1 and Its Receptor Are Associated with the Risk of Age Related Macular Degeneration

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. We have shown previously that mice deficient in monocyte chemoattractant protein-1 (MCP1/CCL2) or its receptor (CCR2) develop the features of AMD in senescent mice, however, the human gene...

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Detalles Bibliográficos
Autores principales: Anand, Akshay, Sharma, Neel Kamal, Gupta, Amod, Prabhakar, Sudesh, Sharma, Suresh Kumar, Singh, Ramandeep, Gupta, Pawan Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503775/
https://www.ncbi.nlm.nih.gov/pubmed/23185481
http://dx.doi.org/10.1371/journal.pone.0049905