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Generation of diploid Pichia pastoris strains by mating and their application for recombinant protein production
BACKGROUND: Yeast mating provides an efficient means for strain and library construction. However, biotechnological applications of mating in the methylotrophic yeast Pichia pastoris have been hampered because of concerns about strain stability of P. pastoris diploids. The aim of the study reported...
Autores principales: | Chen, Ming-Tang, Lin, Song, Shandil, Ishaan, Andrews, Dewan, Stadheim, Terrance A, Choi, Byung-Kwon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503796/ https://www.ncbi.nlm.nih.gov/pubmed/22748191 http://dx.doi.org/10.1186/1475-2859-11-91 |
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