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Rhodopsin Gene Expression Determines Rod Outer Segment Size and Rod Cell Resistance to a Dominant-Negative Neurodegeneration Mutant
Two outstanding unknowns in the biology of photoreceptors are the molecular determinants of cell size, which is remarkably uniform among mammalian species, and the mechanisms of rod cell death associated with inherited neurodegenerative blinding diseases such as retinitis pigmentosa. We have address...
Autores principales: | Price, Brandee A., Sandoval, Ivette M., Chan, Fung, Nichols, Ralph, Roman-Sanchez, Ramon, Wensel, Theodore G., Wilson, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503812/ https://www.ncbi.nlm.nih.gov/pubmed/23185477 http://dx.doi.org/10.1371/journal.pone.0049889 |
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