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Hypoxia Inhibits Hypertrophic Differentiation and Endochondral Ossification in Explanted Tibiae

PURPOSE: Hypertrophic differentiation of growth plate chondrocytes induces angiogenesis which alleviates hypoxia normally present in cartilage. In the current study, we aim to determine whether alleviation of hypoxia is merely a downstream effect of hypertrophic differentiation as previously describ...

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Detalles Bibliográficos
Autores principales:	Leijten, Jeroen C. H., Moreira Teixeira, Liliana S., Landman, Ellie B. M., van Blitterswijk, Clemens A., Karperien, Marcel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503827/ https://www.ncbi.nlm.nih.gov/pubmed/23185479 http://dx.doi.org/10.1371/journal.pone.0049896

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