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Multiple-Clone Activation of Hypnozoites Is the Leading Cause of Relapse in Plasmodium vivax Infection

BACKGROUND: Plasmodium vivax infection is characterized by a dormant hepatic stage, the hypnozoite that is activated at varying periods of time after clearance of the primary acute blood-stage, resulting in relapse. Differentiation between treatment failure and new infections requires characterizati...

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Detalles Bibliográficos
Autores principales:	de Araujo, Flávia Carolina F., de Rezende, Antônio Mauro, Fontes, Cor Jesus F., Carvalho, Luzia Helena, Alves de Brito, Cristiana F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503861/ https://www.ncbi.nlm.nih.gov/pubmed/23185469 http://dx.doi.org/10.1371/journal.pone.0049871

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